Drug interactions
Chlordiazepoxide + Fleroxacin
Severity: Minor
Chlordiazepoxide and Fleroxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones such as fleroxacin may slightly reduce clearance of some benzodiazepines, potentially prolonging sedation. The effect is likely small and fleroxacin is not widely available.
What this interaction means in plain words
Chlordiazepoxide and Fleroxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible inhibition of hepatic metabolism of chlordiazepoxide.
What to do
Monitor for increased drowsiness and reduce the chlordiazepoxide dose if sedation develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlordiazepoxide
Frequently asked questions
Can I take Chlordiazepoxide with Fleroxacin?
MediHelp rates the interaction as minor. Chlordiazepoxide and Fleroxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones such as fleroxacin may slightly reduce clearance of some benzodiazepines, potentially prolonging sedation. The effect is likely small and fleroxacin is not widely available.
How serious is the interaction between Chlordiazepoxide and Fleroxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased drowsiness and reduce the chlordiazepoxide dose if sedation develops.
What other medicines interact with Chlordiazepoxide?
MediHelp also lists interactions of Chlordiazepoxide with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide page.
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