Drug interactions
Choline magnesium trisalicylate + Hydrochlorothiazide-olmesartan
Severity: Minor
Choline magnesium trisalicylate and Hydrochlorothiazide-olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Choline magnesium trisalicylate is a non-acetylated salicylate with less prostaglandin inhibition than other NSAIDs, so the effect on olmesartan and hydrochlorothiazide is smaller, though high doses may still affect renal function and blood pressure control in susceptible patients.
What this interaction means in plain words
Choline magnesium trisalicylate and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak renal prostaglandin inhibition may modestly oppose ARB and diuretic effects.
What to do
Monitor blood pressure and renal function if high doses are used regularly, especially in older or volume-depleted patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Hydrochlorothiazide-olmesartan?
MediHelp rates the interaction as minor. Choline magnesium trisalicylate and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Choline magnesium trisalicylate is a non-acetylated salicylate with less prostaglandin inhibition than other NSAIDs, so the effect on olmesartan and hydrochlorothiazide is smaller, though high doses may still affect renal function and blood pressure control in susceptible patients.
How serious is the interaction between Choline magnesium trisalicylate and Hydrochlorothiazide-olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and renal function if high doses are used regularly, especially in older or volume-depleted patients.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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