Drug interactions
Choline magnesium trisalicylate + Lithium
Severity: Minor
Choline magnesium trisalicylate and Lithium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Non-acetylated salicylates generally have little effect on serum lithium levels, unlike many other NSAIDs. A clinically significant rise is unlikely but not excluded at high doses.
What this interaction means in plain words
Choline magnesium trisalicylate and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Minimal effect on renal prostaglandin-mediated lithium clearance.
What to do
No routine adjustment is needed. Check serum lithium when starting regular high-dose therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Lithium?
MediHelp rates the interaction as minor. Choline magnesium trisalicylate and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Non-acetylated salicylates generally have little effect on serum lithium levels, unlike many other NSAIDs. A clinically significant rise is unlikely but not excluded at high doses.
How serious is the interaction between Choline magnesium trisalicylate and Lithium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check serum lithium when starting regular high-dose therapy.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
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