Drug interactions
Cinnamon + Glibenclamide
Severity: Minor
Cinnamon and Glibenclamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cinnamon may have modest glucose-lowering effects and could add to glyburide, slightly raising hypoglycemia risk. Clinical evidence is limited and inconsistent.
What this interaction means in plain words
Cinnamon and Glibenclamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive insulin-sensitizing effect.
What to do
Monitor blood glucose if cinnamon supplements are taken regularly in large amounts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glibenclamide
- Bosentan + Glibenclamide Contraindicated
- Cholic acid + Glibenclamide Major
- Ciprofloxacin + Glibenclamide Major
- Clarithromycin + Glibenclamide Major
- Fluconazole + Glibenclamide Major
- Glibenclamide + Insulin degludec-liraglutide Major
Frequently asked questions
Can I take Cinnamon with Glibenclamide?
MediHelp rates the interaction as minor. Cinnamon and Glibenclamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon may have modest glucose-lowering effects and could add to glyburide, slightly raising hypoglycemia risk. Clinical evidence is limited and inconsistent.
How serious is the interaction between Cinnamon and Glibenclamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if cinnamon supplements are taken regularly in large amounts.
What other medicines interact with Glibenclamide?
MediHelp also lists interactions of Glibenclamide with, for example, Bosentan, Cholic acid, Ciprofloxacin. The full list is on the Glibenclamide page.
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