Drug interactions
Ciprofibrate + Insulin neutral human
Severity: Moderate
Ciprofibrate and Insulin neutral human: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fibrates can improve insulin sensitivity and glucose control, and may increase the glucose-lowering effect of insulin. Hypoglycemia has been reported, particularly in patients with low albumin or renal impairment.
What this interaction means in plain words
Ciprofibrate and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Fibrates activate PPAR-alpha, which may improve insulin sensitivity and add to insulin's effect; the exact mechanism of hypoglycemia is not fully established.
What to do
Monitor blood glucose when starting or stopping ciprofibrate. Lower the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin neutral human
Frequently asked questions
Can I take Ciprofibrate with Insulin neutral human?
MediHelp rates the interaction as moderate. Ciprofibrate and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fibrates can improve insulin sensitivity and glucose control, and may increase the glucose-lowering effect of insulin. Hypoglycemia has been reported, particularly in patients with low albumin or renal impairment.
How serious is the interaction between Ciprofibrate and Insulin neutral human?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping ciprofibrate. Lower the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
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