Drug interactions
Citalopram + Lamotrigine
Severity: Minor
Citalopram and Lamotrigine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The two drugs may add to drowsiness and psychomotor slowing, but no important interaction is established. Combined use is common in mood disorders and is generally well tolerated.
What this interaction means in plain words
Citalopram and Lamotrigine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Citalopram belongs to Central Nervous System; Lamotrigine belongs to Central Nervous System.
Why it happens
Possible additive CNS effects; no clear pharmacokinetic mechanism is established.
What to do
No dose adjustment is routinely needed. Monitor for excess sedation or dizziness after starting either drug.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Other interactions of Lamotrigine
Frequently asked questions
Can I take Citalopram with Lamotrigine?
MediHelp rates the interaction as minor. Citalopram and Lamotrigine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The two drugs may add to drowsiness and psychomotor slowing, but no important interaction is established. Combined use is common in mood disorders and is generally well tolerated.
How serious is the interaction between Citalopram and Lamotrigine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is routinely needed. Monitor for excess sedation or dizziness after starting either drug.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
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