Drug interactions
Citalopram + Olodaterol inhaled
Severity: Moderate
Citalopram and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citalopram prolongs the QT interval in a dose-dependent manner, and beta2 agonists can cause hypokalemia and cardiac stimulation. Together they may raise the risk of ventricular arrhythmia, although inhaled olodaterol has low systemic exposure at standard doses.
What this interaction means in plain words
Citalopram and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-agonist-mediated cardiac stimulation and hypokalemia.
What to do
Use the approved olodaterol dose and monitor heart rate, palpitations and potassium in patients with cardiac risk factors. Obtain an ECG if symptoms occur or other QT-prolonging drugs are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Citalopram and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Citalopram prolongs the QT interval in a dose-dependent manner, and beta2 agonists can cause hypokalemia and cardiac stimulation. Together they may raise the risk of ventricular arrhythmia, although inhaled olodaterol has low systemic exposure at standard doses.
How serious is the interaction between Citalopram and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the approved olodaterol dose and monitor heart rate, palpitations and potassium in patients with cardiac risk factors. Obtain an ECG if symptoms occur or other QT-prolonging drugs are present.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
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