Drug interactions
Citalopram + Telmisartan-amlodipine
Severity: Minor
Citalopram and Telmisartan-amlodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citalopram, like other SSRIs, can cause hyponatremia through SIADH, and the risk is greater in older adults. Telmisartan-amlodipine itself does not strongly lower sodium, so the interaction is minor in this combination, but the antihypertensive may add to volume or electrolyte disturbance in vulnerable patients.
What this interaction means in plain words
Citalopram and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Citalopram belongs to Central Nervous System; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Citalopram-induced SIADH may be compounded by other factors affecting sodium and volume balance; the antihypertensive contributes little directly.
What to do
Check serum sodium after starting citalopram in elderly patients or those on other sodium-lowering drugs. Investigate any confusion, nausea or falls promptly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Telmisartan-amlodipine?
MediHelp rates the interaction as minor. Citalopram and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Citalopram, like other SSRIs, can cause hyponatremia through SIADH, and the risk is greater in older adults. Telmisartan-amlodipine itself does not strongly lower sodium, so the interaction is minor in this combination, but the antihypertensive may add to volume or electrolyte disturbance in vulnerable patients.
How serious is the interaction between Citalopram and Telmisartan-amlodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum sodium after starting citalopram in elderly patients or those on other sodium-lowering drugs. Investigate any confusion, nausea or falls promptly.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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