Drug interactions
Clemastine + Passion flower
Severity: Minor
Clemastine and Passion flower: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Passion flower has mild sedative and anxiolytic effects and may add to clemastine drowsiness. This may impair alertness and psychomotor performance.
What this interaction means in plain words
Clemastine and Passion flower have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depression, probably through GABAergic activity of the herb.
What to do
Advise patients to watch for added drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clemastine
Frequently asked questions
Can I take Clemastine with Passion flower?
MediHelp rates the interaction as minor. Clemastine and Passion flower have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Passion flower has mild sedative and anxiolytic effects and may add to clemastine drowsiness. This may impair alertness and psychomotor performance.
How serious is the interaction between Clemastine and Passion flower?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for added drowsiness and avoid driving if affected.
What other medicines interact with Clemastine?
MediHelp also lists interactions of Clemastine with, for example, Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal. The full list is on the Clemastine page.
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