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Drug interactions

Dabigatran + Ginko biloba

Severity: Moderate

Dabigatran and Ginko biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dabigatran is an oral direct thrombin inhibitor, and ginkgo may mildly impair platelet function. The combination could raise bleeding risk, though evidence consists mostly of theory and isolated reports.

What this interaction means in plain words

Dabigatran and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive pharmacodynamic effects of thrombin inhibition and ginkgolide antagonism of platelet-activating factor.

What to do

Advise patients to avoid ginkgo while taking dabigatran. If used, monitor for bruising, bleeding and hemoglobin changes.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dabigatran with Ginko biloba?

MediHelp rates the interaction as moderate. Dabigatran and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dabigatran is an oral direct thrombin inhibitor, and ginkgo may mildly impair platelet function. The combination could raise bleeding risk, though evidence consists mostly of theory and isolated reports.

How serious is the interaction between Dabigatran and Ginko biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid ginkgo while taking dabigatran. If used, monitor for bruising, bleeding and hemoglobin changes.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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