Drug interactions
Danazol + Empagliflozin-linagliptin
Severity: Minor
Danazol and Empagliflozin-linagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol is a weak CYP3A4 inhibitor and may slightly raise linagliptin levels. Danazol can also impair glucose tolerance, which may matter more than the pharmacokinetic effect.
What this interaction means in plain words
Danazol and Empagliflozin-linagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 inhibition by danazol reduces linagliptin metabolism.
What to do
No dose change is needed for linagliptin. Monitor blood glucose during danazol therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-linagliptin
Frequently asked questions
Can I take Danazol with Empagliflozin-linagliptin?
MediHelp rates the interaction as minor. Danazol and Empagliflozin-linagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol is a weak CYP3A4 inhibitor and may slightly raise linagliptin levels. Danazol can also impair glucose tolerance, which may matter more than the pharmacokinetic effect.
How serious is the interaction between Danazol and Empagliflozin-linagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed for linagliptin. Monitor blood glucose during danazol therapy.
What other medicines interact with Empagliflozin-linagliptin?
MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.
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