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Drug interactions

Danazol + Insulin aspart

Severity: Moderate

Danazol and Insulin aspart: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Danazol, an androgenic agent, can cause insulin resistance and impaired glucose tolerance, so insulin needs may change. Glycemic control can be unpredictable.

What this interaction means in plain words

Danazol and Insulin aspart can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Androgenic effects alter insulin sensitivity and glucose metabolism, modifying insulin requirements.

What to do

Monitor blood glucose when danazol is started or stopped and adjust insulin dose accordingly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Danazol with Insulin aspart?

MediHelp rates the interaction as moderate. Danazol and Insulin aspart can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danazol, an androgenic agent, can cause insulin resistance and impaired glucose tolerance, so insulin needs may change. Glycemic control can be unpredictable.

How serious is the interaction between Danazol and Insulin aspart?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when danazol is started or stopped and adjust insulin dose accordingly.

What other medicines interact with Insulin aspart?

MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.

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