Drug interactions
Deferasirox + Ethinylestradiol
Severity: Moderate
Deferasirox and Ethinylestradiol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may lower ethinylestradiol exposure, which could reduce the reliability of hormonal contraception and cause breakthrough bleeding.
What this interaction means in plain words
Deferasirox and Ethinylestradiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Deferasirox induces CYP3A4, increasing metabolism of ethinylestradiol.
What to do
Advise an additional non-hormonal contraceptive method and monitor for breakthrough bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Ethinylestradiol?
MediHelp rates the interaction as moderate. Deferasirox and Ethinylestradiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox may lower ethinylestradiol exposure, which could reduce the reliability of hormonal contraception and cause breakthrough bleeding.
How serious is the interaction between Deferasirox and Ethinylestradiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional non-hormonal contraceptive method and monitor for breakthrough bleeding.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
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