Drug interactions
Deferasirox + Ferrous fumarate
Severity: Moderate
Deferasirox and Ferrous fumarate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox binds iron in the gut, so oral iron is poorly absorbed. The agents oppose each other therapeutically.
What this interaction means in plain words
Deferasirox and Ferrous fumarate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Ferrous fumarate belongs to Miscellaneous.
Why it happens
Deferasirox chelates iron in the gastrointestinal tract, forming unabsorbable complexes.
What to do
Avoid oral iron in patients on deferasirox unless iron deficiency is documented. Monitor ferritin and hemoglobin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous fumarate
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Ferrous fumarate?
MediHelp rates the interaction as moderate. Deferasirox and Ferrous fumarate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox binds iron in the gut, so oral iron is poorly absorbed. The agents oppose each other therapeutically.
How serious is the interaction between Deferasirox and Ferrous fumarate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid oral iron in patients on deferasirox unless iron deficiency is documented. Monitor ferritin and hemoglobin.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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