Drug interactions
Deferasirox + Iron dextran complex
Severity: Moderate
Deferasirox and Iron dextran complex: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox is an iron chelator and counteracts iron supplementation. Iron dextran is mostly given parenterally, so the pair is therapeutically opposed rather than an absorption interaction.
What this interaction means in plain words
Deferasirox and Iron dextran complex can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism: deferasirox chelates iron supplied by iron dextran.
What to do
Avoid concurrent use unless clearly indicated; monitor ferritin and transferrin saturation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Iron dextran complex?
MediHelp rates the interaction as moderate. Deferasirox and Iron dextran complex can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox is an iron chelator and counteracts iron supplementation. Iron dextran is mostly given parenterally, so the pair is therapeutically opposed rather than an absorption interaction.
How serious is the interaction between Deferasirox and Iron dextran complex?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use unless clearly indicated; monitor ferritin and transferrin saturation.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
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