Drug interactions
Deferoxamine + Ferrous fumarate
Severity: Moderate
Deferoxamine and Ferrous fumarate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferoxamine binds iron and promotes its removal, which counteracts iron supplementation. Oral iron is largely bound and poorly absorbed.
What this interaction means in plain words
Deferoxamine and Ferrous fumarate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferoxamine belongs to Miscellaneous; Ferrous fumarate belongs to Miscellaneous.
Why it happens
Deferoxamine chelates iron, reducing absorption and increasing elimination.
What to do
Avoid iron supplements during chelation unless deficiency is confirmed. Monitor iron indices.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous fumarate
Other interactions of Deferoxamine
Frequently asked questions
Can I take Deferoxamine with Ferrous fumarate?
MediHelp rates the interaction as moderate. Deferoxamine and Ferrous fumarate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferoxamine binds iron and promotes its removal, which counteracts iron supplementation. Oral iron is largely bound and poorly absorbed.
How serious is the interaction between Deferoxamine and Ferrous fumarate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid iron supplements during chelation unless deficiency is confirmed. Monitor iron indices.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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