Drug interactions
Deferoxamine + Ferrous sulfate
Severity: Moderate
Deferoxamine and Ferrous sulfate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferoxamine binds iron and removes it from the body, which opposes the purpose of iron supplementation. Oral iron is mostly bound in the gut and not absorbed if deferoxamine is present there.
What this interaction means in plain words
Deferoxamine and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferoxamine belongs to Miscellaneous; Ferrous sulfate belongs to Miscellaneous.
Why it happens
Deferoxamine chelates iron, reducing its absorption and promoting its elimination.
What to do
Avoid iron supplementation during chelation therapy unless a deficiency is confirmed. Monitor iron indices and adjust therapy accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous sulfate
Other interactions of Deferoxamine
Frequently asked questions
Can I take Deferoxamine with Ferrous sulfate?
MediHelp rates the interaction as moderate. Deferoxamine and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferoxamine binds iron and removes it from the body, which opposes the purpose of iron supplementation. Oral iron is mostly bound in the gut and not absorbed if deferoxamine is present there.
How serious is the interaction between Deferoxamine and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid iron supplementation during chelation therapy unless a deficiency is confirmed. Monitor iron indices and adjust therapy accordingly.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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