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Drug interactions

Devil's claw + Fenoprofen

Severity: Minor

Devil's claw and Fenoprofen: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Devil's claw is used for pain and has been reported to have some antiplatelet effects, with isolated reports of bleeding. Combined with an NSAID, there may be a modest additive bleeding risk.

What this interaction means in plain words

Devil's claw and Fenoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive antiplatelet effect; evidence is limited.

What to do

Ask patients about herbal use and advise reporting bruising or bleeding. Avoid combining with other anticoagulant drugs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Devil's claw with Fenoprofen?

MediHelp rates the interaction as minor. Devil's claw and Fenoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw is used for pain and has been reported to have some antiplatelet effects, with isolated reports of bleeding. Combined with an NSAID, there may be a modest additive bleeding risk.

How serious is the interaction between Devil's claw and Fenoprofen?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise reporting bruising or bleeding. Avoid combining with other anticoagulant drugs.

What other medicines interact with Fenoprofen?

MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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