Drug interactions
Devil's claw + Heparin
Severity: Moderate
Devil's claw and Heparin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has been linked to rare bleeding events and may have mild antiplatelet activity. Taken with heparin it could add modestly to bleeding risk, though evidence is limited.
What this interaction means in plain words
Devil's claw and Heparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet effect; the mechanism is not well characterized.
What to do
Recommend avoiding devil's claw during heparin therapy. If it is used, monitor for bleeding and check coagulation parameters.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Heparin
- Defibrotide + Heparin Contraindicated
- Heparin + Ketorolac Contraindicated
- Heparin + Oritavancin Contraindicated
- Acemetacin + Heparin Major
- Acetylsalicylic acid + Heparin Major
- Alteplase + Heparin Major
Frequently asked questions
Can I take Devil's claw with Heparin?
MediHelp rates the interaction as moderate. Devil's claw and Heparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Devil's claw has been linked to rare bleeding events and may have mild antiplatelet activity. Taken with heparin it could add modestly to bleeding risk, though evidence is limited.
How serious is the interaction between Devil's claw and Heparin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Recommend avoiding devil's claw during heparin therapy. If it is used, monitor for bleeding and check coagulation parameters.
What other medicines interact with Heparin?
MediHelp also lists interactions of Heparin with, for example, Defibrotide, Ketorolac, Oritavancin. The full list is on the Heparin page.
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