Drug interactions
Devil's claw + Insulin lispro
Severity: Minor
Devil's claw and Insulin lispro: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has shown possible glucose-lowering activity in animal data, so additive hypoglycemia with insulin is theoretical. Human data are lacking.
What this interaction means in plain words
Devil's claw and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive hypoglycemic effect; mechanism not established.
What to do
Monitor blood glucose when the herb is started or stopped and adjust insulin only if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin lispro
Frequently asked questions
Can I take Devil's claw with Insulin lispro?
MediHelp rates the interaction as minor. Devil's claw and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has shown possible glucose-lowering activity in animal data, so additive hypoglycemia with insulin is theoretical. Human data are lacking.
How serious is the interaction between Devil's claw and Insulin lispro?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when the herb is started or stopped and adjust insulin only if needed.
What other medicines interact with Insulin lispro?
MediHelp also lists interactions of Insulin lispro with, for example, Alogliptin-pioglitazone, Ethanol, Metreleptin. The full list is on the Insulin lispro page.
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