Drug interactions
Dexfenfluramine + Insulin neutral human
Severity: Moderate
Dexfenfluramine and Insulin neutral human: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexfenfluramine may improve peripheral glucose utilization and can add to the glucose-lowering effect of insulin. This raises the risk of hypoglycemia in insulin-treated patients. The drug has been withdrawn from most markets.
What this interaction means in plain words
Dexfenfluramine and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Serotonergic anorectic action increases peripheral glucose uptake, producing additive glucose lowering with insulin.
What to do
Monitor blood glucose closely and reduce the insulin dose as needed if this drug is used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin neutral human
Frequently asked questions
Can I take Dexfenfluramine with Insulin neutral human?
MediHelp rates the interaction as moderate. Dexfenfluramine and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexfenfluramine may improve peripheral glucose utilization and can add to the glucose-lowering effect of insulin. This raises the risk of hypoglycemia in insulin-treated patients. The drug has been withdrawn from most markets.
How serious is the interaction between Dexfenfluramine and Insulin neutral human?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely and reduce the insulin dose as needed if this drug is used.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
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