Drug interactions
Dexfenfluramine + Terbutaline
Severity: Moderate
Dexfenfluramine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexfenfluramine is a serotonergic anorectic and terbutaline is a beta-2 agonist with sympathomimetic effects. Together they may produce additive cardiovascular stimulation such as tachycardia, palpitations or raised blood pressure.
What this interaction means in plain words
Dexfenfluramine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic sympathomimetic and cardiovascular effects.
What to do
Monitor heart rate and blood pressure when the combination is used. Reduce the terbutaline dose or stop one agent if tachycardia or hypertension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Dexfenfluramine with Terbutaline?
MediHelp rates the interaction as moderate. Dexfenfluramine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexfenfluramine is a serotonergic anorectic and terbutaline is a beta-2 agonist with sympathomimetic effects. Together they may produce additive cardiovascular stimulation such as tachycardia, palpitations or raised blood pressure.
How serious is the interaction between Dexfenfluramine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when the combination is used. Reduce the terbutaline dose or stop one agent if tachycardia or hypertension develops.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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