Drug interactions
Dextroamphetamine + Diamorphine
Severity: Minor
Dextroamphetamine and Diamorphine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diamorphine is a sedating opioid and dextroamphetamine a stimulant. The stimulant may mask sedation but does not reverse respiratory depression. Together they can also strain the cardiovascular system, particularly in recreational use.
What this interaction means in plain words
Dextroamphetamine and Diamorphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing CNS pharmacodynamic effects; the interaction is poorly characterized.
What to do
Monitor respiratory rate and sedation and do not use stimulant alertness as a guide to opioid safety.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Diamorphine?
MediHelp rates the interaction as minor. Dextroamphetamine and Diamorphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Diamorphine is a sedating opioid and dextroamphetamine a stimulant. The stimulant may mask sedation but does not reverse respiratory depression. Together they can also strain the cardiovascular system, particularly in recreational use.
How serious is the interaction between Dextroamphetamine and Diamorphine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory rate and sedation and do not use stimulant alertness as a guide to opioid safety.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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