Drug interactions
Dextroamphetamine + Dopexamine
Severity: Moderate
Dextroamphetamine and Dopexamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopexamine is a catecholamine-like agent with beta2 and dopaminergic activity, and amphetamine adds indirect sympathomimetic stimulation. Together they may cause greater tachycardia, arrhythmia and blood pressure changes than either drug alone.
What this interaction means in plain words
Dextroamphetamine and Dopexamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic effects from direct receptor agonism by dopexamine and amphetamine-induced catecholamine release.
What to do
Monitor ECG, heart rate and blood pressure continuously during dopexamine infusion in patients taking amphetamine. Titrate dopexamine to the lowest effective rate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Dopexamine?
MediHelp rates the interaction as moderate. Dextroamphetamine and Dopexamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopexamine is a catecholamine-like agent with beta2 and dopaminergic activity, and amphetamine adds indirect sympathomimetic stimulation. Together they may cause greater tachycardia, arrhythmia and blood pressure changes than either drug alone.
How serious is the interaction between Dextroamphetamine and Dopexamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure continuously during dopexamine infusion in patients taking amphetamine. Titrate dopexamine to the lowest effective rate.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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