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Drug interactions

Dextroamphetamine + Formoterol

Severity: Moderate

Dextroamphetamine and Formoterol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both drugs have sympathomimetic activity, so combined use can raise heart rate and blood pressure and may provoke palpitations, tremor or arrhythmias. The effect is most relevant in patients with cardiovascular disease or hyperthyroidism.

What this interaction means in plain words

Dextroamphetamine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dextroamphetamine belongs to Central Nervous System; Formoterol belongs to Respiratory.

Evidence level: Moderate

Why it happens

Additive adrenergic stimulation: beta-2 receptor agonism by formoterol plus amphetamine-mediated catecholamine release.

What to do

Monitor heart rate, blood pressure and cardiac symptoms, especially at initiation or dose increases. Use the lowest effective formoterol dose and reassess in patients with cardiovascular disease.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dextroamphetamine with Formoterol?

MediHelp rates the interaction as moderate. Dextroamphetamine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sympathomimetic activity, so combined use can raise heart rate and blood pressure and may provoke palpitations, tremor or arrhythmias. The effect is most relevant in patients with cardiovascular disease or hyperthyroidism.

How serious is the interaction between Dextroamphetamine and Formoterol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and cardiac symptoms, especially at initiation or dose increases. Use the lowest effective formoterol dose and reassess in patients with cardiovascular disease.

What other medicines interact with Formoterol?

MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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