Drug interactions
Dextroamphetamine + Meprobamate
Severity: Minor
Dextroamphetamine and Meprobamate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meprobamate is a sedative-anxiolytic and dextroamphetamine is a stimulant, so they have opposing CNS effects. Stimulation may mask sedation, and the net effect is unpredictable, with a risk of impaired judgement or misuse.
What this interaction means in plain words
Dextroamphetamine and Meprobamate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing pharmacodynamic CNS effects; no pharmacokinetic interaction is established.
What to do
Counsel the patient about unpredictable alertness and avoid driving until the response is known. Reassess the need for both drugs if sedation or agitation occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Meprobamate?
MediHelp rates the interaction as minor. Dextroamphetamine and Meprobamate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Meprobamate is a sedative-anxiolytic and dextroamphetamine is a stimulant, so they have opposing CNS effects. Stimulation may mask sedation, and the net effect is unpredictable, with a risk of impaired judgement or misuse.
How serious is the interaction between Dextroamphetamine and Meprobamate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about unpredictable alertness and avoid driving until the response is known. Reassess the need for both drugs if sedation or agitation occurs.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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