Drug interactions
Dextroamphetamine + Metaproterenol
Severity: Moderate
Dextroamphetamine and Metaproterenol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have sympathomimetic activity, so combined use can increase heart rate and blood pressure and may provoke palpitations, tremor or arrhythmias. The risk is greater in patients with cardiovascular disease.
What this interaction means in plain words
Dextroamphetamine and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation: amphetamine releases catecholamines while metaproterenol directly stimulates beta-adrenoceptors.
What to do
Monitor heart rate, blood pressure and rhythm, especially in patients with heart disease. Use the lowest effective bronchodilator dose and consider alternatives if cardiovascular symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Metaproterenol?
MediHelp rates the interaction as moderate. Dextroamphetamine and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sympathomimetic activity, so combined use can increase heart rate and blood pressure and may provoke palpitations, tremor or arrhythmias. The risk is greater in patients with cardiovascular disease.
How serious is the interaction between Dextroamphetamine and Metaproterenol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and rhythm, especially in patients with heart disease. Use the lowest effective bronchodilator dose and consider alternatives if cardiovascular symptoms occur.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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