Drug interactions
Dextroamphetamine + Papaveretum
Severity: Moderate
Dextroamphetamine and Papaveretum: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Papaveretum contains opium alkaloids including morphine and causes sedation and respiratory depression. Dextroamphetamine may mask drowsiness but does not prevent respiratory depression.
What this interaction means in plain words
Dextroamphetamine and Papaveretum can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Opposing CNS pharmacodynamic effects; stimulant activity may obscure opioid sedation.
What to do
Monitor respiratory rate and oxygenation during opioid use. Do not assume adequate arousal means safe opioid dosing.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Papaveretum?
MediHelp rates the interaction as moderate. Dextroamphetamine and Papaveretum can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Papaveretum contains opium alkaloids including morphine and causes sedation and respiratory depression. Dextroamphetamine may mask drowsiness but does not prevent respiratory depression.
How serious is the interaction between Dextroamphetamine and Papaveretum?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory rate and oxygenation during opioid use. Do not assume adequate arousal means safe opioid dosing.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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