Drug interactions
Dextroamphetamine + Quazepam
Severity: Minor
Dextroamphetamine and Quazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quazepam is a long-acting benzodiazepine hypnotic and dextroamphetamine is a stimulant, so their CNS effects oppose each other. Stimulation may mask residual sedation, which can leave psychomotor impairment unnoticed.
What this interaction means in plain words
Dextroamphetamine and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing CNS pharmacodynamic effects; no pharmacokinetic interaction is established.
What to do
Counsel patients on possible next-day impairment despite feeling alert. Separate dosing times to avoid evening stimulant dosing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Quazepam?
MediHelp rates the interaction as minor. Dextroamphetamine and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quazepam is a long-acting benzodiazepine hypnotic and dextroamphetamine is a stimulant, so their CNS effects oppose each other. Stimulation may mask residual sedation, which can leave psychomotor impairment unnoticed.
How serious is the interaction between Dextroamphetamine and Quazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients on possible next-day impairment despite feeling alert. Separate dosing times to avoid evening stimulant dosing.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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