Drug interactions
Dextroamphetamine + Scullcap
Severity: Minor
Dextroamphetamine and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Skullcap is used as a mild sedative herb, whereas dextroamphetamine is stimulating. Any interaction is theoretical, and some skullcap products have been associated with hepatotoxicity.
What this interaction means in plain words
Dextroamphetamine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible opposing CNS effects; the mechanism is not established.
What to do
Ask about herbal supplement use and monitor alertness and sleep. No dose change is typically required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Scullcap?
MediHelp rates the interaction as minor. Dextroamphetamine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Skullcap is used as a mild sedative herb, whereas dextroamphetamine is stimulating. Any interaction is theoretical, and some skullcap products have been associated with hepatotoxicity.
How serious is the interaction between Dextroamphetamine and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal supplement use and monitor alertness and sleep. No dose change is typically required.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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