Drug interactions
Dextroamphetamine + Triclofos
Severity: Minor
Dextroamphetamine and Triclofos: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dextroamphetamine may counteract the sedative-hypnotic effect of triclofos, whose active metabolite is trichloroethanol. The result can be reduced hypnotic efficacy without removal of impairment risk.
What this interaction means in plain words
Dextroamphetamine and Triclofos have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing CNS stimulant and sedative effects; no established pharmacokinetic mechanism.
What to do
Give dextroamphetamine early in the day and review the need for the hypnotic. Monitor sleep and daytime function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Triclofos?
MediHelp rates the interaction as minor. Dextroamphetamine and Triclofos have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dextroamphetamine may counteract the sedative-hypnotic effect of triclofos, whose active metabolite is trichloroethanol. The result can be reduced hypnotic efficacy without removal of impairment risk.
How serious is the interaction between Dextroamphetamine and Triclofos?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give dextroamphetamine early in the day and review the need for the hypnotic. Monitor sleep and daytime function.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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