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Drug interactions

Dextroamphetamine + Yerba mate

Severity: Minor

Dextroamphetamine and Yerba mate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Yerba mate contains caffeine and related xanthines that can add to the stimulant effects of dextroamphetamine. This may cause greater insomnia, tachycardia, anxiety or blood pressure elevation.

What this interaction means in plain words

Dextroamphetamine and Yerba mate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive central and sympathetic stimulation from xanthines and amphetamine.

What to do

Advise moderating yerba mate intake. Monitor sleep, heart rate and blood pressure.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dextroamphetamine with Yerba mate?

MediHelp rates the interaction as minor. Dextroamphetamine and Yerba mate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Yerba mate contains caffeine and related xanthines that can add to the stimulant effects of dextroamphetamine. This may cause greater insomnia, tachycardia, anxiety or blood pressure elevation.

How serious is the interaction between Dextroamphetamine and Yerba mate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise moderating yerba mate intake. Monitor sleep, heart rate and blood pressure.

What other medicines interact with Dextroamphetamine?

MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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