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Drug interactions

Diethylpropion + Terbutaline

Severity: Moderate

Diethylpropion and Terbutaline: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Diethylpropion is an amphetamine-like anorectic with sympathomimetic effects, as is terbutaline. Together they may cause additive increases in heart rate and blood pressure, along with tremor, anxiety and palpitations.

What this interaction means in plain words

Diethylpropion and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive pharmacodynamic sympathomimetic effects.

What to do

Monitor heart rate and blood pressure, and avoid the combination in patients with arrhythmia or uncontrolled hypertension. Reduce doses if adrenergic symptoms emerge.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Diethylpropion with Terbutaline?

MediHelp rates the interaction as moderate. Diethylpropion and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Diethylpropion is an amphetamine-like anorectic with sympathomimetic effects, as is terbutaline. Together they may cause additive increases in heart rate and blood pressure, along with tremor, anxiety and palpitations.

How serious is the interaction between Diethylpropion and Terbutaline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and avoid the combination in patients with arrhythmia or uncontrolled hypertension. Reduce doses if adrenergic symptoms emerge.

What other medicines interact with Terbutaline?

MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.

Full monographs, dosing and an interaction checker in the MediHelp app

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