Drug interactions
Dong quai + Ketorolac
Severity: Moderate
Dong quai and Ketorolac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin derivatives and has been associated with increased INR in patients on warfarin. It may add to the bleeding tendency caused by ketorolac, though documentation is limited.
What this interaction means in plain words
Dong quai and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Coumarin-type constituents and possible antiplatelet effects of dong quai may add to ketorolac's platelet inhibition.
What to do
Advise patients to avoid dong quai while taking ketorolac, and monitor for bleeding if both are used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Dong quai with Ketorolac?
MediHelp rates the interaction as moderate. Dong quai and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin derivatives and has been associated with increased INR in patients on warfarin. It may add to the bleeding tendency caused by ketorolac, though documentation is limited.
How serious is the interaction between Dong quai and Ketorolac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while taking ketorolac, and monitor for bleeding if both are used.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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