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Drug interactions

Droperidol + Levosalbutamol

Severity: Moderate

Droperidol and Levosalbutamol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Droperidol prolongs the QT interval and carries a risk of torsades de pointes. Levosalbutamol may add to this risk through tachycardia and beta-2 mediated hypokalemia.

What this interaction means in plain words

Droperidol and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive effects on cardiac repolarization, with beta-2 agonist induced hypokalemia contributing to QT risk.

What to do

Check potassium and magnesium and obtain an ECG before use in patients with risk factors. Monitor the ECG during and after droperidol administration.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Droperidol with Levosalbutamol?

MediHelp rates the interaction as moderate. Droperidol and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Droperidol prolongs the QT interval and carries a risk of torsades de pointes. Levosalbutamol may add to this risk through tachycardia and beta-2 mediated hypokalemia.

How serious is the interaction between Droperidol and Levosalbutamol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and obtain an ECG before use in patients with risk factors. Monitor the ECG during and after droperidol administration.

What other medicines interact with Levosalbutamol?

MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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