Drug interactions
Echinacea + Muromonab cd3
Severity: Moderate
Echinacea and Muromonab cd3: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea might theoretically counteract the T-cell suppression produced by muromonab-CD3 in transplant rejection treatment. A resulting loss of effect could threaten the graft. Evidence is theoretical only.
What this interaction means in plain words
Echinacea and Muromonab cd3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Theoretical pharmacodynamic antagonism between immune stimulation and CD3-mediated T-cell depletion.
What to do
Avoid echinacea during muromonab-CD3 therapy. Monitor graft function and rejection markers.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Frequently asked questions
Can I take Echinacea with Muromonab cd3?
MediHelp rates the interaction as moderate. Echinacea and Muromonab cd3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea might theoretically counteract the T-cell suppression produced by muromonab-CD3 in transplant rejection treatment. A resulting loss of effect could threaten the graft. Evidence is theoretical only.
How serious is the interaction between Echinacea and Muromonab cd3?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid echinacea during muromonab-CD3 therapy. Monitor graft function and rejection markers.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Antithymocyte globulin rabbit. The full list is on the Echinacea page.
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