Drug interactions
Epinephrine + Epinephrine racemic
Severity: Moderate
Epinephrine and Epinephrine racemic: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine contains epinephrine, so combining it with epinephrine by another route adds to total adrenergic load. Tachycardia, hypertension, arrhythmias and lower serum potassium may result.
What this interaction means in plain words
Epinephrine and Epinephrine racemic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Duplicate therapy producing additive adrenergic receptor stimulation.
What to do
Avoid concurrent use unless clinically needed and count both doses toward total exposure. Monitor ECG, blood pressure and potassium if both are given.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Epinephrine
- Epinephrine + Isocarboxazid Contraindicated
- Epinephrine + Phenelzine Contraindicated
- Epinephrine + Tranylcypromine Contraindicated
- Acebutolol + Epinephrine Major
- Amitriptyline + Epinephrine Major
- Amoxapine + Epinephrine Major
Frequently asked questions
Can I take Epinephrine with Epinephrine racemic?
MediHelp rates the interaction as moderate. Epinephrine and Epinephrine racemic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Racemic epinephrine contains epinephrine, so combining it with epinephrine by another route adds to total adrenergic load. Tachycardia, hypertension, arrhythmias and lower serum potassium may result.
How serious is the interaction between Epinephrine and Epinephrine racemic?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use unless clinically needed and count both doses toward total exposure. Monitor ECG, blood pressure and potassium if both are given.
What other medicines interact with Epinephrine?
MediHelp also lists interactions of Epinephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Epinephrine page.
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