Drug interactions
Epinephrine + Indacaterol inhaled
Severity: Moderate
Epinephrine and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol is a long-acting beta-2 agonist, and epinephrine can add to its cardiovascular and metabolic effects. Tachycardia, palpitations, tremor, hypertension and hypokalemia may be more pronounced.
What this interaction means in plain words
Epinephrine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic receptor stimulation.
What to do
Monitor heart rate, blood pressure and serum potassium when epinephrine is given to patients using indacaterol. Do not stack other long-acting beta agonists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Epinephrine
- Epinephrine + Isocarboxazid Contraindicated
- Epinephrine + Phenelzine Contraindicated
- Epinephrine + Tranylcypromine Contraindicated
- Acebutolol + Epinephrine Major
- Amitriptyline + Epinephrine Major
- Amoxapine + Epinephrine Major
Frequently asked questions
Can I take Epinephrine with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Epinephrine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol is a long-acting beta-2 agonist, and epinephrine can add to its cardiovascular and metabolic effects. Tachycardia, palpitations, tremor, hypertension and hypokalemia may be more pronounced.
How serious is the interaction between Epinephrine and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and serum potassium when epinephrine is given to patients using indacaterol. Do not stack other long-acting beta agonists.
What other medicines interact with Epinephrine?
MediHelp also lists interactions of Epinephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Epinephrine page.
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