Drug interactions
Escitalopram + Pindolol
Severity: Minor
Escitalopram and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol is partly metabolized by CYP2D6, which escitalopram inhibits weakly, so exposure could rise slightly. Pindolol has also been used to augment SSRIs, and a significant adverse interaction is not expected.
What this interaction means in plain words
Escitalopram and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP2D6 inhibition by escitalopram may modestly reduce pindolol clearance.
What to do
No adjustment is usually needed. Monitor for bradycardia and hypotension.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Pindolol?
MediHelp rates the interaction as minor. Escitalopram and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pindolol is partly metabolized by CYP2D6, which escitalopram inhibits weakly, so exposure could rise slightly. Pindolol has also been used to augment SSRIs, and a significant adverse interaction is not expected.
How serious is the interaction between Escitalopram and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is usually needed. Monitor for bradycardia and hypotension.
What other medicines interact with Escitalopram?
MediHelp also lists interactions of Escitalopram with, for example, Cisapride, Citalopram, Isocarboxazid. The full list is on the Escitalopram page.
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