Drug interactions
Escitalopram + Vilanterol / fluticasone furoate inhaled
Severity: Moderate
Escitalopram and Vilanterol / fluticasone furoate inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol is a long-acting beta-agonist with potential effects on heart rhythm and QT interval. Escitalopram prolongs the QT interval in a dose-related way. Systemic vilanterol exposure from inhalation is low, so the risk is modest but may matter in cardiac patients.
What this interaction means in plain words
Escitalopram and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and possible beta-agonist-related hypokalemia and arrhythmia potentiation.
What to do
Use recommended inhaler doses and monitor for palpitations or arrhythmia. Consider ECG and potassium checks in patients with cardiac disease or other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as moderate. Escitalopram and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vilanterol is a long-acting beta-agonist with potential effects on heart rhythm and QT interval. Escitalopram prolongs the QT interval in a dose-related way. Systemic vilanterol exposure from inhalation is low, so the risk is modest but may matter in cardiac patients.
How serious is the interaction between Escitalopram and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use recommended inhaler doses and monitor for palpitations or arrhythmia. Consider ECG and potassium checks in patients with cardiac disease or other QT risk factors.
What other medicines interact with Escitalopram?
MediHelp also lists interactions of Escitalopram with, for example, Cisapride, Citalopram, Isocarboxazid. The full list is on the Escitalopram page.
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