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Drug interactions

Ethanol + Pimozide

Severity: Moderate

Ethanol and Pimozide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Alcohol and pimozide both depress the CNS, so drinking can increase drowsiness, impair coordination and judgement, and raise the risk of accidents. Alcohol may also worsen orthostatic hypotension.

What this interaction means in plain words

Ethanol and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Additive CNS depressant effects.

What to do

Advise patients to avoid alcohol during pimozide treatment and to avoid driving or hazardous tasks if they have consumed it.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ethanol with Pimozide?

MediHelp rates the interaction as moderate. Ethanol and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol and pimozide both depress the CNS, so drinking can increase drowsiness, impair coordination and judgement, and raise the risk of accidents. Alcohol may also worsen orthostatic hypotension.

How serious is the interaction between Ethanol and Pimozide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol during pimozide treatment and to avoid driving or hazardous tasks if they have consumed it.

What other medicines interact with Pimozide?

MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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