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Drug interactions

Ethinylestradiol + Green tea

Severity: Minor

Ethinylestradiol and Green tea: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ethinylestradiol can reduce caffeine clearance, so caffeine from green tea may have a stronger or longer effect in women taking estrogen-containing contraceptives. This may cause jitteriness, insomnia or palpitations with high intake.

What this interaction means in plain words

Ethinylestradiol and Green tea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Moderate

Why it happens

Ethinylestradiol inhibits CYP1A2-mediated caffeine metabolism.

What to do

Advise moderating green tea and caffeine intake if symptoms of excess stimulation occur. No change to contraceptive therapy is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ethinylestradiol with Green tea?

MediHelp rates the interaction as minor. Ethinylestradiol and Green tea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ethinylestradiol can reduce caffeine clearance, so caffeine from green tea may have a stronger or longer effect in women taking estrogen-containing contraceptives. This may cause jitteriness, insomnia or palpitations with high intake.

How serious is the interaction between Ethinylestradiol and Green tea?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise moderating green tea and caffeine intake if symptoms of excess stimulation occur. No change to contraceptive therapy is needed.

What other medicines interact with Green tea?

MediHelp also lists interactions of Green tea with, for example, Adenosine, Benzphetamine, Bortezomib. The full list is on the Green tea page.

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