Drug interactions
Exenatide + Mestranol
Severity: Minor
Exenatide and Mestranol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Exenatide slows gastric emptying, which may delay or reduce the absorption of oral drugs that depend on rapid uptake, such as contraceptives. Estrogens may also modestly impair glucose tolerance, which could weaken glycemic control.
What this interaction means in plain words
Exenatide and Mestranol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Delayed gastric emptying from exenatide alters oral drug absorption, and estrogens have mild effects on glucose tolerance.
What to do
Advise taking the oral contraceptive at least 1 hour before exenatide injection. Monitor glycemic control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Exenatide and Mestranol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Exenatide
- Chlorpropamide + Exenatide Major
- Asenapine + Exenatide Moderate
- Betamethasone + Exenatide Moderate
- Chlorothiazide + Exenatide Moderate
- Clozapine + Exenatide Moderate
- Cortisone + Exenatide Moderate
Frequently asked questions
Can I take Exenatide with Mestranol?
MediHelp rates the interaction as minor. Exenatide and Mestranol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Exenatide slows gastric emptying, which may delay or reduce the absorption of oral drugs that depend on rapid uptake, such as contraceptives. Estrogens may also modestly impair glucose tolerance, which could weaken glycemic control.
How serious is the interaction between Exenatide and Mestranol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise taking the oral contraceptive at least 1 hour before exenatide injection. Monitor glycemic control.
What other medicines interact with Exenatide?
MediHelp also lists interactions of Exenatide with, for example, Chlorpropamide, Asenapine, Betamethasone. The full list is on the Exenatide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
