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Drug interactions

Fenoprofen + Ginkgo biloba

Severity: Moderate

Fenoprofen and Ginkgo biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ginkgo inhibits platelet-activating factor and there are case reports of bleeding, including intracranial hemorrhage, with antithrombotic drugs. Combined with an NSAID, bleeding risk may be raised.

What this interaction means in plain words

Fenoprofen and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive antiplatelet effect through platelet-activating factor antagonism and cyclooxygenase inhibition.

What to do

Advise avoiding ginkgo while taking fenoprofen, or monitor for bleeding and stop ginkgo before surgery.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fenoprofen with Ginkgo biloba?

MediHelp rates the interaction as moderate. Fenoprofen and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo inhibits platelet-activating factor and there are case reports of bleeding, including intracranial hemorrhage, with antithrombotic drugs. Combined with an NSAID, bleeding risk may be raised.

How serious is the interaction between Fenoprofen and Ginkgo biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo while taking fenoprofen, or monitor for bleeding and stop ginkgo before surgery.

What other medicines interact with Fenoprofen?

MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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