Drug interactions
Fenoprofen + Horse chestnut seed
Severity: Minor
Fenoprofen and Horse chestnut seed: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Horse chestnut contains aescin and coumarin derivatives that may have anticoagulant or antiplatelet effects, so bleeding risk may be modestly increased with NSAIDs. Evidence is limited.
What this interaction means in plain words
Fenoprofen and Horse chestnut seed have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effect on coagulation and platelet function.
What to do
Counsel patients to report bleeding or bruising and avoid combined use around surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Frequently asked questions
Can I take Fenoprofen with Horse chestnut seed?
MediHelp rates the interaction as minor. Fenoprofen and Horse chestnut seed have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Horse chestnut contains aescin and coumarin derivatives that may have anticoagulant or antiplatelet effects, so bleeding risk may be modestly increased with NSAIDs. Evidence is limited.
How serious is the interaction between Fenoprofen and Horse chestnut seed?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report bleeding or bruising and avoid combined use around surgery.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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