Drug interactions
Fenoprofen + Icosapent
Severity: Minor
Fenoprofen and Icosapent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl may prolong bleeding time modestly, and NSAIDs also impair platelet function. Together they may slightly increase bleeding risk.
What this interaction means in plain words
Fenoprofen and Icosapent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive platelet inhibition from omega-3 effects and cyclooxygenase blockade.
What to do
Monitor for bleeding periodically, especially if other antithrombotics are also used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Frequently asked questions
Can I take Fenoprofen with Icosapent?
MediHelp rates the interaction as minor. Fenoprofen and Icosapent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Icosapent ethyl may prolong bleeding time modestly, and NSAIDs also impair platelet function. Together they may slightly increase bleeding risk.
How serious is the interaction between Fenoprofen and Icosapent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding periodically, especially if other antithrombotics are also used.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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