Drug interactions
Fenoprofen + Neomycin po
Severity: Minor
Fenoprofen and Neomycin po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin is poorly absorbed, and NSAIDs may reduce renal clearance of aminoglycosides mainly in preterm neonates. In adults with intact gut and kidneys the effect is negligible.
What this interaction means in plain words
Fenoprofen and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
NSAID-mediated reduction in renal clearance of absorbed aminoglycoside, relevant mainly in immature kidneys.
What to do
No action is generally needed in adults. In neonates or those with renal impairment or gut inflammation, monitor renal function and aminoglycoside exposure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Frequently asked questions
Can I take Fenoprofen with Neomycin po?
MediHelp rates the interaction as minor. Fenoprofen and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin is poorly absorbed, and NSAIDs may reduce renal clearance of aminoglycosides mainly in preterm neonates. In adults with intact gut and kidneys the effect is negligible.
How serious is the interaction between Fenoprofen and Neomycin po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally needed in adults. In neonates or those with renal impairment or gut inflammation, monitor renal function and aminoglycoside exposure.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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