Drug interactions
Fenoprofen + Pindolol
Severity: Moderate
Fenoprofen and Pindolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs can reduce the blood pressure lowering effect of beta-blockers such as pindolol, especially with prolonged use. Control of hypertension may be lost.
What this interaction means in plain words
Fenoprofen and Pindolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID inhibition of vasodilatory prostaglandins and sodium and water retention.
What to do
Monitor blood pressure when starting or stopping fenoprofen and adjust antihypertensive therapy if needed. Use the shortest NSAID course possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Frequently asked questions
Can I take Fenoprofen with Pindolol?
MediHelp rates the interaction as moderate. Fenoprofen and Pindolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs can reduce the blood pressure lowering effect of beta-blockers such as pindolol, especially with prolonged use. Control of hypertension may be lost.
How serious is the interaction between Fenoprofen and Pindolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when starting or stopping fenoprofen and adjust antihypertensive therapy if needed. Use the shortest NSAID course possible.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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