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Drug interactions

Ferrous sulfate + Thyroid desiccated

Severity: Moderate

Ferrous sulfate and Thyroid desiccated: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Iron binds thyroid hormones in the gut and reduces their absorption. This can lead to loss of thyroid control and a rising TSH.

What this interaction means in plain words

Ferrous sulfate and Thyroid desiccated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Iron forms insoluble complexes with thyroid hormones in the gut, reducing absorption.

What to do

Separate doses by at least 4 hours. Check TSH about 6 to 8 weeks after starting or changing iron.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ferrous sulfate with Thyroid desiccated?

MediHelp rates the interaction as moderate. Ferrous sulfate and Thyroid desiccated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds thyroid hormones in the gut and reduces their absorption. This can lead to loss of thyroid control and a rising TSH.

How serious is the interaction between Ferrous sulfate and Thyroid desiccated?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 4 hours. Check TSH about 6 to 8 weeks after starting or changing iron.

What other medicines interact with Ferrous sulfate?

MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.

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