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Drug interactions

Feverfew + Ginko biloba

Severity: Moderate

Feverfew and Ginko biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Feverfew inhibits platelet aggregation in laboratory studies, and ginkgo may also affect platelets. Together they may modestly raise the risk of bruising or bleeding.

What this interaction means in plain words

Feverfew and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive antiplatelet effects, with feverfew inhibiting platelet aggregation and secretion and ginkgo antagonizing PAF.

What to do

Avoid combining them in patients on anticoagulants or antiplatelets or with bleeding disorders. Stop both about two weeks before elective surgery.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Feverfew with Ginko biloba?

MediHelp rates the interaction as moderate. Feverfew and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Feverfew inhibits platelet aggregation in laboratory studies, and ginkgo may also affect platelets. Together they may modestly raise the risk of bruising or bleeding.

How serious is the interaction between Feverfew and Ginko biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining them in patients on anticoagulants or antiplatelets or with bleeding disorders. Stop both about two weeks before elective surgery.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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